Roose Organoid D2B Core
The Roose Organoid D2B (Disease-to-Biology) Core at UCSF provides patient-derived organoids (PDOs), organoid expertise, and translational infrastructure to accelerate collaborative research and precision medicine approaches.
Collaborations:
We welcome collaborations with: Private clients, Foundations, Biotech and Pharma, AI-driven biomedical companies. For external collaborations and partnership inquiries, please contact: Jeroen Roose, PhD
UCSF Investigators. UCSF researchers can access the Organoid D2B Core through: UCSF iLab – Organoid Core: https://ucsf.ilab.agilent.com/service_center/show_external/6099?name=organoid-core
For project discussions and onboarding, please contact: Michelle Gbenedio, Organoid D2B Core Manager.
Current Capabilities:
Biobanked Patient-Derived Organoids (PDOs). Access to a growing living biobank of normal and disease-derived human organoids. PDO Generation & Biobanking. Generation, expansion, characterization, and cryopreservation of new PDOs from clinical samples. Spectral Flow Cytometry for PDOs. Patented high-dimensional spectral flow platform for quantitative single-cell analysis of organoid systems. Project Consultation & Experimental Design. Guidance on organoid implementation, translational workflows, and study design. Training & Technical Support. Hands-on training in PDO culture, expansion, maintenance, and downstream analyses. Touchdown Organoid Culture Space. Dedicated tissue culture space for investigators initiating organoid-based projects. NAMs & Grant Support. Boilerplate NIH materials and strategic guidance for investigators incorporating NAMs (New Approach Methodologies) into grant applications.
